{"id":2995,"date":"2026-02-16T09:18:38","date_gmt":"2026-02-16T09:18:38","guid":{"rendered":"https:\/\/en.ige.uobaghdad.edu.iq\/?p=2995"},"modified":"2026-02-27T09:26:41","modified_gmt":"2026-02-27T09:26:41","slug":"the-institute-of-genetic-engineering-and-biotechnology-for-postgraduate-studies-received-an-official-delegation-from-the-college-of-health-and-medical-technologies-al-kut-university-as-part-of-effort","status":"publish","type":"post","link":"https:\/\/en.ige.uobaghdad.edu.iq\/?p=2995","title":{"rendered":"Genetic Engineering Discusses a Computational and Molecular Study of the Most Abundant Non-Coding RNAs and Their Effect on the Gene Expression of HIF-1 in Breast Cancer Patients."},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]<\/p>\n<div class=\"flex flex-col text-sm pb-25\">\n<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto scroll-mt-(--header-height)\" dir=\"auto\" tabindex=\"-1\" data-turn-id=\"703a8832-e05a-4eb7-adfb-5e4f5c1551bc\" data-testid=\"conversation-turn-39\" data-scroll-anchor=\"false\" data-turn=\"user\"><\/article>\n<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" tabindex=\"-1\" data-turn-id=\"request-WEB:50d9a80f-0b05-4461-b8f9-0c209387e371-19\" data-testid=\"conversation-turn-40\" data-scroll-anchor=\"true\" data-turn=\"assistant\">\n<div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] @w-sm\/main:[--thread-content-margin:--spacing(6)] @w-lg\/main:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:40rem] @w-lg\/main:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\" tabindex=\"-1\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"0711019d-5eee-4511-80c4-214c8a84654b\" data-message-model-slug=\"gpt-5-mini\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[1px]\">\n<div class=\"markdown prose dark:prose-invert w-full wrap-break-word light markdown-new-styling\">\n<p style=\"text-align: justify;\" data-start=\"0\" data-end=\"143\"><span style=\"font-size: 18px;\">The <span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">Institute of Genetic Engineering and Biotechnology for Postgraduate Studies<\/span><\/span> discussed the PhD dissertation submitted by doctoral candidate Hatim Mohammed Hadeed, entitled:<\/span><\/p>\n<p style=\"text-align: justify;\" data-start=\"145\" data-end=\"292\"><span style=\"font-size: 18px;\">\u201cComputational and Molecular Study of the Most Abundant Non-Coding RNAs and Their Effect on HIF-1 Gene Expression in Breast Cancer Patients\u201d,<\/span><\/p>\n<p style=\"text-align: justify;\" data-start=\"294\" data-end=\"419\"><span style=\"font-size: 18px;\">under the supervision of Professor Dr. Marib Nazih Rasheed and external supervisor Professor Dr. Ahmed Abdul Jabbar Suleiman.<\/span><\/p>\n<p style=\"text-align: justify;\" data-start=\"421\" data-end=\"663\"><span style=\"font-size: 18px;\">The study aimed to identify miRNA and lncRNA molecules involved in hypoxia at different stages of breast cancer and to select the most influential ones to investigate their role in HIF-1A gene expression during cancer progression.<\/span><\/p>\n<p style=\"text-align: justify;\" data-start=\"665\" data-end=\"1003\"><span style=\"font-size: 18px;\">The study recommended highlighting the potential role of miRNAs, lncRNAs, and HIF-1A as promising biomarkers in breast cancer. Based on these results, it suggested further exploration of miRNAs and lncRNAs to validate the association between these ncRNAs and HIF-1A expression in both primary and metastatic breast cancer samples.<\/span><\/p>\n<p style=\"text-align: justify;\" data-start=\"1005\" data-end=\"1408\"><span style=\"font-size: 18px;\">It also emphasized the need for additional studies in larger, multicenter cohorts to confirm the diagnostic and predictive value of these markers across diverse patient groups. Integrating miRNA, lncRNA, and HIF-1A expression profiles with established clinical-pathological features and molecular markers (such as ER, PR, and HER2) could enhance their predictive accuracy and clinical relevance.<\/span><\/p>\n<p style=\"text-align: justify;\" data-start=\"1410\" data-end=\"1621\" data-is-last-node=\"\" data-is-only-node=\"\"><span style=\"font-size: 18px;\">Finally, the study stressed the importance of applying advanced bioinformatics and multi-omics approaches to identify regulatory networks involving miRNAs, lncRNAs, HIF-1A, and their downstream target genes.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"z-0 flex min-h-[46px] justify-start\"><\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<div class=\"pointer-events-none h-px w-px absolute bottom-0\" aria-hidden=\"true\" data-edge=\"true\"><\/div>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;2998&#8243; img_size=&#8221;large&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221; css=&#8221;&#8221;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;2999&#8243; img_size=&#8221;large&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221; css=&#8221;&#8221;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;3000&#8243; img_size=&#8221;large&#8221; alignment=&#8221;center&#8221; onclick=&#8221;img_link_large&#8221; css=&#8221;&#8221;][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text] The Institute of Genetic Engineering and Biotechnology for Postgraduate Studies discussed the PhD dissertation submitted by doctoral candidate Hatim &#8230; <\/p>\n","protected":false},"author":37,"featured_media":2997,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"","footnotes":""},"categories":[14,17,7],"tags":[],"class_list":["post-2995","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-archives","category-last-news","category-a-a"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - 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