The Institute of Genetic Engineering and Biotechnology for Postgraduate Studies discussed the Higher Diploma report submitted by student Samah Sabah Turki, entitled:
“Chronic Urinary Tract Infections and Bladder Cancer”,
under the supervision of Assistant Professor Dr. Ashwaq Basim Jasim, in the institute’s discussion hall.
The report aimed to study the multifactorial relationship between chronic urinary tract infections and bladder cancer, including chronic inflammation, oxidative stress, bacterial virulence, and host immune responses.
The study highlighted that microbial imbalance promotes chronic inflammation, which is associated with an increased risk of bladder cancer through mechanisms involving inflammatory and immune responses, as well as microbial toxin production.
The study recommended that identifying bacterial species, immune markers, and epigenetic changes in urine could contribute to early diagnosis of bladder cancer and risk assessment. It also emphasized that advanced molecular techniques, such as metagenomics and methylation pattern analysis, offer promising prospects in personalized medicine and understanding host–microbe interactions in bladder carcinogenesis.
